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☆ Here are Tuesday's biggest analyst calls: Apple, Nvidia, Amazon, Tesla, Seagate, Boston Beer, Planet Fitness & more
▼ + stars: | 2024-05-14 | by ( Michael Bloom | ) www.cnbc.com time to read: +6 min

Wells Fargo reiterates Nvidia as overweight Wells increased its price target on Nvidia to $1,150 per share from $970. Jefferies upgrades Boston Beer to buy from hold Jefferies said in its upgrade of the beverage company that it sees "multiple expansion." Bank of America reiterates Apple as buy Bank of America said it's sticking with its buy rating on shares of Apple. JPMorgan upgrades Planet Fitness to overweight from neutral JPMorgan said in its has increased confidence in Planet Fitness' growth. JPMorgan upgrades Vtex to overweight from neutral JPMorgan said it sees an attractive entry point for the software-as-a-service company.

Persons: Tesla, Goldman Sachs, Goldman, it's, Wells, ests, Jefferies, Beer, Roth, Morgan Stanley, GXO's, Baird, Oppenheimer, Edwards Organizations: Barclays, Oncology, Fulcrum Therapeutics, ISI, Nvidia, Jefferies, Boston Beer, GXO Logistics, Bank of America, Apple, HSBC, Citi, Weatherford, Energy, JPMorgan, LT, Fortrea Holdings, Edison International, RBC, North, Deutsche Bank, Amazon, Deutsche, Western Digital, Seagate Locations: China, North America

☆ US regional banks are still under pressure. That’s likely to continue
▼ + stars: | 2024-04-18 | by ( Krystal Hur | ) edition.cnn.com time to read: +6 min

New York CNN —Despite overcoming a crisis in 2023, the pain isn’t over for America’s regional banks. Shares of New York Community Bank have tumbled 71%, Bank OZK shares have slid 16% and Webster Financial shares have lost 11%. Regional banks reported wide losses on their profits during the first quarter. PNC projects that its net interest income will fall between 4% to 5% in 2024 from last year. “I’m worried about a handful of [regional banks],” Bair told CNBC on Tuesday.

Persons: that’s, Jerome Powell, “, ” Powell, Sheila Bair, “ I’m, ” Bair, ” Tesla, Tesla, Elon Musk, Chris Isidore, Musk, Chancellor Kathaleen McCormick, Read, Samantha Delouya, —, Maximilian Kotz, Leonie Wenz, Noah Diffenbaugh Organizations: CNN Business, Bell, New York CNN, Regional Banking, New York Community Bank, Bank OZK, Webster Financial, PNC Financial, T Bank, US Bancorp, Citizens, PNC, Valley Bank, Signature Bank, First Republic Bank, Federal Reserve, Wilson Center, Federal Deposit Insurance Corporation, CNBC, Tesla, Securities and Exchange Commission, United Nations, Potsdam, Climate, CNN, Stanford University Locations: New York, Delaware, ” Delaware

☆ Climate change and global warming come with increasing economic cost to individuals
▼ + stars: | 2024-04-17 | by ( Samantha Delouya | ) edition.cnn.com time to read: +5 min

However, they say immediate actions to reduce climate change could stem some losses in the longer term. Noah Diffenbaugh, a professor and environmental researcher at Stanford University, said the economic damage from climate change will take different shapes. Researchers estimated it would cost the global economy $6 trillion by 2050 to comply with the Paris Climate Agreement—the international agreement among nearly 200 nations to tackle climate change—compared to the study’s estimated $38 trillion economic damage due to climate change. “That’s what’s likely to happen from the global warming that’s already occurred and what’s likely to happen even for small increments of global warming.”The Nature study estimated the economic damage of different regions. The ICF paper said price hikes on essential elements of the cost of living in the US will add up due to climate change.

Persons: –, Maximilian Kotz, Leonie Wenz, Noah Diffenbaugh, It’s, Wenz, Bernardo Bastien, Bastien, ” Bastien, “, ”, “ That’s, what’s, won’t Organizations: CNN, United Nations, Potsdam, Climate, Stanford University, Scripps Institute of Oceanography, University of California Locations: Nature, Paris, University of California San Diego, California, North America, Europe, South Asia, Africa, United States

☆ Climate change and extreme heat will drive inflation higher, study says
▼ + stars: | 2024-03-25 | by ( Aruni Soni | ) www.businessinsider.com time to read: +2 min

Global warming and extreme heat will drive inflation higher, a new study says. In the next decade, climate change could bump up food inflation by as much as 3.23% per year and headline inflation by as much as 1.18%. "A worst-case emission scenario would cause pressures on food inflation exceeding 4% [per year] across large parts of the world." According to a new study published in the journal Communications Earth & Environment, the effects of global warming and extreme heat are expected to create persistent increases in headline and food inflation. Related storiesThat could bump up food inflation by as much as 3.23% a year on average globally, and push headline inflation up by as much as 1.18% in the coming decade.

Organizations: Service, Environment, Potsdam Institute, Climate Impact Research, European Central Bank Locations: Africa, South America

☆ For century-old Mack Trucks, the 18-wheeled, bulldog-big rig future is still going to be EV
▼ + stars: | 2024-03-03 | by ( Bob Woods | ) www.cnbc.com time to read: +6 min

Mack Trucks, founded in Brooklyn, New York, in 1900, is renowned for its 18-wheelers, diesel-powered big rigs with a trademark bulldog mounted on the hood. Purchase-making decisions are distinct for consumer and commercial markets, a difference reflected in last year's EV sales results within both sectors and outlooks for future growth. EV sales increased year over year by 40% in the fourth quarter, yet were down from 49% in the third quarter. Cox expects this year's EV sales to reach 1.5 million, about 36% higher than last year. Eighty EV truck deployments were cataloged in 2020, and those deployments jumped to 1,948 in 2022.

Persons: Mack Trucks, Mack, Jonathan Randall, Kelley, Cox, Tesla, EVs, Randall, BEV, Ann Rundle, Rundle Organizations: Mack Trucks North, Sweden's Volvo Group, Volvo Trucks, Volvo, U.S, EV, Ford, GM, EDF, American Truck Dealers Association, ACT Research, ICE Locations: Brooklyn , New York, —, New York City, Miami , Florida, Mack Trucks North America, Greensboro , North Carolina, Paris, U.S, United States

☆ Starboard Value’s Jeffrey Smith firms up activist bet on GoDaddy, trims winning Salesforce stake
▼ + stars: | 2024-02-15 | by ( Yun Li | ) www.cnbc.com time to read: +1 min

Starboard Value's Jeff Smith added to his GoDaddy holding while trimming his lucrative activist bet in Salesforce , according to a new regulatory filing. The hedge fund increased its stake in GoDaddy to nearly $925 million, making the web services company its biggest holding. Starboard continued to trim its stake in customer relations management software company Salesforce , which in 2022, he took an activist stake in. The filing also reveals a few new stakes for Starboard, including News Corp and Fortrea . CNBC had already reported on these stakes when Smith appeared at a conference in last year.

Persons: Jeff Smith, Smith, He's Organizations: Wharton, News Corp, Fortrea, CNBC Locations: Salesforce, GoDaddy, New York

☆ Time to say 'the F-words'? A fossil fuel fight takes center stage at the COP28 climate summit
▼ + stars: | 2023-12-04 | by ( Sam Meredith | ) www.cnbc.com time to read: +5 min

Sultan al-Jaber, president of the UNFCCC COP28 climate conference, speaks during day two of the summit on Dec. 2, 2023 in Dubai, United Arab Emirates. Sean Gallup | Getty Images News | Getty ImagesDubai, UNITED ARAB EMIRATES — A fight over the future of fossil fuels has been thrust into the global spotlight at the COP28 climate summit. "Unabated" fossil fuels are largely understood to be produced and used without substantial reductions in the amount of emitted greenhouse gases. "[It is] important to say that more fossil fuels equal more loss and damage, so these two issues are actually quite intertwined." Notably, at last year's COP27 conference in Egypt, more than 80 countries supported a fossil fuel phase-out commitment in the final agreement.

Persons: Sultan al, Jaber, Sean Gallup, Johan Rockstrom, There's, Darren Woods, Catherine Abreu, Abreu Organizations: Getty, Getty Images, UNITED, EMIRATES, Potsdam Institute, Climate, Climate Impact Research, CNBC, AG, United Arab, Oil, Exxon Mobil Locations: Dubai, United Arab Emirates, Getty Images Dubai, COP28, Salzgitter, Germany, Russia, Egypt

☆ Here are Tuesday's biggest analyst calls: Nvidia, Tesla, Apple, Disney, Microsoft, AMD, Amazon, Adobe & more
▼ + stars: | 2023-11-14 | by ( Michael Bloom | ) www.cnbc.com time to read: +6 min

Morgan Stanley downgrades Freyr Battery to equal weight from overweight Morgan Stanley said the battery maker faces "significant challenges." Barclays upgrades Fortrea to overweight from equal weight Barclays said in its upgrade of the health contract research company that it sees improved bookings. Barclays upgrades Mosaic and Nutrien to overweight from underweight Barclays upgraded several potash and aggriculture companies and said a compelling entry point. " Morgan Stanley reiterates Tesla as overweight Morgan Stanley said it's standing by its overweight rating on shares of Tesla . Barclays reiterates Disney as equal weight Barclays said it's having trouble finding upside for Disney shares.

Persons: Wells, Needham, Docebo, Morgan Stanley downgrades Freyr, Morgan Stanley, FREY, Andrew Stanleick, Bernstein, Redburn, Goldman Sachs, Goldman, it's, Baird, Kraft Heinz, Miguel Patricio, " Roth, Marvell, Roth, Tesla, laggards, Evercore, TD Cowen, Cowen, We've Organizations: Microsoft, TAM, Deutsche Bank, Deutsche, UBS, Barclays, Mosaic, NTR, ICL, OW, UW, JPMorgan, Apple, Nvidia, Aspen Technology, Kraft, Marvell Technology, Devices, Tesla, Adobe, Disney Locations: BeautyHealth, U.S

Steve Beshear – faces Republican Attorney General Daniel Cameron, a protege of Senate Minority Leader Mitch McConnell. In Mississippi, Republican Lynn Fitch is seeking a second term against Greta Kemp Martin, the litigation director of Disability Rights Mississippi. Democratic attorney Lindsey Cheek won the other runoff slot by taking 23% of the all-party primary vote. In Mississippi, Republican incumbent Michael Watson is seeking a second term and should easily defeat Democrat Ty Pinkins. She will face Democratic attorney, accountant, and small business owner Gwen Collins-Greenup, who finished second in the primary.

Persons: — it’s, Kentuckians, Andy Beshear, Jeff Landry, Beshear, Steve Beshear –, Daniel Cameron, Mitch McConnell, Kentucky’s, He’s, Cameron, Tate Reeves, Brandon Presley, Elvis Presley, Presley, Reeves, Democrat hasn’t, Jim Hood, Glenn Youngkin’s, Winsome Sears, Youngkin, Phil Murphy, Democratic Sen, Robert Menendez, Joe Biden, Max Baer, Carolyn Carluccio, Daniel McCaffery, Donald Trump, wouldn’t, Roe, Wade, Ohio’s, Sen, Bernie Sanders of, Janet Mills, Russell Coleman, McConnell, Pamela Stevenson, Republican Lynn Fitch, Greta Kemp Martin, Fitch, Liz Murrill, Landry, Lindsey Cheek, Michael Adams, Buddy Wheatley, Adams, Michael Watson, Ty Pinkins, Shuwaski Young, Young, Kyle Ardoin, Nancy Landry, Gwen Collins, Greenup Organizations: Democratic Gov, Democratic, Republican, Gubernatorial, Gov, Lean Democratic, Republican Gov, Public Service Commission, Democrat, Mississippi, Public, Impact Research, Lean Republican, State Legislative, Virginia, GOP, Senate, Republicans, House, George Mason University, Assembly, , New Jersey Republicans, Pleas, Superior Court, Ohio, Sierra Club, AFL, of Commerce, Avangrid Inc, Trump, Air Force, Disability Rights Mississippi, State, Iraq Locations: Mississippi, Virginia, Republican . New Jersey, Garden, Pennsylvania, Ohio, Maine, In Kentucky, Republican Mississippi, U.S, Northern Virginia, Richmond, Hampton Roads, Washington, New Jersey, , New Jersey, Montgomery County, In Ohio, Bernie Sanders of Vermont, Massachusetts, Texas, Kentucky, Louisiana, State Kentucky, In Mississippi

☆ IQVIA cuts annual profit forecast on slow demand for medtech, analytics services
▼ + stars: | 2023-11-01 | by ( ) www.reuters.com time to read: +2 min

Nov 1 (Reuters) - IQVIA Holdings (IQV.N) cut its full-year profit forecast on Wednesday, citing weakness in demand for its analytics and medical technology solutions along with the impact of a stronger U.S. dollar. Thermo Fisher signaled that the demand slump from biotech clients for its contract research services could extend into the next year due to rising interest rates and a persistent funding crunch. On an adjusted basis, IQVIA reported a profit of $2.49 per share for the third quarter, topping estimates of $2.44 per share. The company now expects full-year adjusted profit to be between $10.16 and $10.23 per share, compared with its prior per-share forecast of $10.26 to $10.56. IQVIA now expects 2023 revenue between $14.89 billion and $14.92 billion, compared with its previous forecast of $15.05 billion to $15.18 billion.

Persons: IQVIA, Fisher, Christy Santhosh, Shweta Agarwal Organizations: IQVIA Holdings, Danaher Corp, Thomson Locations: Durham , North Carolina, Bengaluru

"Short term, if you're visiting a smaller biotech customer, what you're seeing is concerns about when the funding environment is going to improve. On the call, finance chief Stephen Williamson said core revenue growth and adjusted profit in 2024 will be similar to that in 2023. It also forecast 2023 adjusted profit of $21.50 per share, below analysts' estimates of $22.28. The medical equipment maker forecast adjusted earnings of $21.75 per share in 2024, short of analysts' estimates by $2.23. Third-quarter revenue of $10.57 billion missed analysts' expectations of $10.60 billion while adjusted profit of $5.69 per share topped estimates of $5.61, according to LSEG data.

Persons: Brian Snyder, Marc Casper, Stephen Williamson, Raymond James, Andrew Cooper, Bhanvi, Shinjini Ganguli, Shounak Dasgupta, Sriraj Organizations: REUTERS, Agilent Technologies, Reuters, Thomson Locations: Waltham , Massachusetts, U.S, China, Bengaluru

☆ Danaher Beats Profit Estimates on Respiratory Testing Demand
▼ + stars: | 2023-10-24 | by ( Oct. | At A.M. | ) www.usnews.com time to read: +2 min

(Reuters) - Danaher on Tuesday beat Wall Street estimates for third-quarter profit as strong demand for its diagnostic tests for respiratory diseases helped soften the blow from weaker sales at the healthcare conglomerate's life-sciences unit. "Revenue in the third quarter came in ahead of our expectations, with Biotechnology performing as anticipated, and higher respiratory testing revenue more than offsetting slightly softer-than-anticipated demand in Life Sciences," Danaher CEO Rainer Blair said in a statement. Rising interest rates squeezed funding needed for drug development programs, weighing on demand for contract research services offered by Danaher and rival Thermo Fisher. On an adjusted basis, Danaher reported a profit per share of $2.02, beating analysts' expectations of $1.87. Third-quarter sales of $6.87 billion also topped estimates of $6.63 billion.

Persons: Rainer Blair, Danaher, Christy Santhosh, Krishna Chandra Eluri Organizations: Reuters, Biotechnology, Life Sciences, Washington D.C, Danaher, Fisher, Applied Solutions

☆ Starboard may be poised to build value amicably at contract research firm Fortrea
▼ + stars: | 2023-10-21 | by ( Kenneth Squire | ) www.cnbc.com time to read: +5 min

CROs work with drug companies through all stages of the drug development process, from drug discovery and preclinical development to Phase I through IV post-approval work. With a material portion of that outsourced, the CRO industry has grown accordingly. So, there are strong secular tailwinds driving growth for the CRO industry, but to be a successful contract research organization, it helps to have global scale. With peer margins and peer multiples, Starboard sees this as a $47 to $72 stock. Elliott Management recently partnered with Patient Square Capital and Veritas Capital to acquire Fortrea peer Syneos Health Inc (SYNH) for $7.1 billion.

Persons: Covance, Fortrea, Tom Pike, Pike, Elliott, Ken Squire Organizations: Fortrea, Labcorp, Development, Elliott Management, Square, Veritas Capital, Inc, pharma, 13D, Fortrea Holdings Locations: Covance, Labcorp, Fortrea

☆ Starboard Value's Jeff Smith unveils his newest ideas, including a push for News Corp spinoff
▼ + stars: | 2023-10-17 | by ( Yun Li | ) www.cnbc.com time to read: +3 min

Starboard Value's Jeff Smith on Tuesday presented his newest investment ideas across different industries. "If management can successfully execute on a margin improvement plan, we believe GoDaddy shareholders will be meaningfully rewarded," he said. GoDaddy shares are up only about 1% this year, significantly underperforming the broader market. "If management can successfully execute on a margin improvement plan, we believe GoDaddy shareholders will be meaningfully rewarded," he said. GoDaddy shares are up only about 1% this year, significantly underperforming the broader market.

Persons: Jeff Smith, Smith, Dow Jones, Fortrea, Jeffrey Smith, David Paul Morris Organizations: 13D, News Corp, Dow, Group, Bloomberg, Getty Locations: New York City, Australia

☆ Stocks making the biggest moves premarket: Wyndham Hotels, Dollar Tree, Johnson & Johnson and more
▼ + stars: | 2023-10-17 | by ( Pia Singh | ) www.cnbc.com time to read: +2 min

Wyndham Hotels & Resorts , Choice Hotels — Choice Hotels dropped 2.3% after the hotel chain proposed buying Wyndham Hotels & Resorts for $90 per share, valuing Wyndham at roughly $7.8 billion. Analysts surveyed by LSEG, formerly Refinitiv, were looking for 82 cents in earnings on $25.14 billion of revenue. Bank of New York Mellon earned $1.22 per share on $4.37 billion in revenue in the quarter, exceeding analysts' estimates on both lines. Johnson & Johnson -- Shares of the multinational drug and medical equipment maker gained nearly 2% after third-quarter earnings and sales topped analyst estimates. Lockheed Martin reported earnings of $6.73 per share, surpassing expectations of $6.67 per share, according to estimates from LSEG.

Persons: Wyndham, Charlotte, Goldman Sachs, Johnson, Lockheed Martin, —, Jesse Pound, Michelle Fox Theobald, Brian Evans Organizations: Wyndham Hotels & Resorts, Bank of America, LSEG, Goldman, Bank of New York Mellon, Johnson, Fortrea Holdings, Wall Street Journal, Lockheed, LSEG . Revenue Locations: Charlotte , NC, LSEG

☆ Stocks making the biggest moves midday: Nvidia, Goldman Sachs, Lockheed Martin and more
▼ + stars: | 2023-10-17 | by ( Hakyung Kim | ) www.cnbc.com time to read: +5 min

The company posted $6.73 in earnings per share on $16.88 billion in revenue. Analysts surveyed by LSEG, formerly known as Refinitiv, had forecast $6.67 in earnings per share on $16.74 billion in revenue. Dollar Tree — The discount retailer jumped 4.8% after getting an upgrade from Goldman Sachs to buy from neutral. Analysts polled by LSEG forecast an adjusted $2.52 in earnings per share and $21.04 billion in revenue. Goldman Sachs earned $5.47 per share on revenue of $11.82 billion, exceeding LSEG estimates.

Persons: Lockheed Martin, chipmakers, Goldman Sachs, Johnson, LSEG, Wyndham, Brian Essex, Hannon Armstrong, Morgan Stanley, Fortrea, Jeff Smith, —, Samantha Subin, Alex Harring, Lisa Kailai Han, Pia Singh, Sarah Min, Tanaya Macheel Organizations: Lockheed, LSEG, Circor, Nvidia, U.S . Department of Commerce, Marvell Technology, Devices, Broadcom, Goldman, Bank of America, Bank of New York Mellon, Wyndham Hotels, Resorts, Wyndham, Choice, JPMorgan, VF Corp, Viasat —, Hannon Armstrong Sustainable Infrastructure Capital, Systems Locations: China

☆ Europe could become energy self-sufficient in $2 trillion push - study
▼ + stars: | 2023-10-04 | by ( ) www.reuters.com time to read: +2 min

[1/2] Electrical power pylons with high-voltage power lines are seen next to wind turbines near Weselitz, Germany November 18, 2022. REUTERS/Lisi Niesner Acquire Licensing RightsFRANKFURT, Oct 5 (Reuters) - Europe could wean itself off fossil fuels and create a self-sustainable energy sector by spending around 2 trillion euros ($2.1 trillion) on solar, wind and other regenerative sources by 2040, according to a new study. The law raises the EU's renewable energy targets, requiring 42.5% of EU energy to be renewable by 2030, replacing a previous 32% target. It said renewable energy supply would need to grow by 20% per year to meet expected power demand by 2030. ($1 = 0.9531 euros)Reporting by Christoph Steitz, Editing by Rachel More and Alex RichardsonOur Standards: The Thomson Reuters Trust Principles.

Persons: Lisi Niesner, Christoph Steitz, Rachel More, Alex Richardson Organizations: REUTERS, Rights, Potsdam Institute, Climate Impact, Reuters, Aquila Capital, Thomson Locations: Weselitz, Germany, Europe, Russian, Ukraine

☆ The IPO market has 'lost a lot of relevance,' says Swiss asset manager Partners Group
▼ + stars: | 2023-09-15 | by ( Lee Ying Shan | ) www.cnbc.com time to read: +3 min

watch nowThe IPO market has lost relevance in the real economy, but there are "absolutely enormous" opportunities in the health-care sector, according to the executive chairman of global private markets firm Partners Group. Private markets are switching places with public markets as the stewards of the real economy. "Private markets are switching places with public markets as the stewards of the real economy," said Partners Group. Partners' Group recorded $142 billion worth of assets under management as of the first half of 2023. Asked whether Partners Group will someday open up the window for retail investors to tap into the private equity market, Meister said it's already happening, marking a "democratization" of the private market industry.

Persons: Steffen Meister, CNBC's Chery Kang, Meister, it's Organizations: Partners, Milken Asia Summit, Bain & Company, Private, CNBC, McKinsey Locations: Singapore

BERLIN, Sept 13 (Reuters) - The Earth's life-support systems are facing greater risks and uncertainties than ever before, with most major safety limits already crossed as a result of planet-wide human interventions, according to a scientific study released on Wednesday. The authors said crossing the boundaries did not represent a tipping point where human civilisation would just crash, but could bring irreversible shifts in the Earth's support systems. "We can think of Earth as a human body, and the planetary boundaries as blood pressure. Over 120/80 does not indicate a certain heart attack but it does raise the risk," Richardson said. "It is a complete failure ...and it's a large risk... We're still following a pathway that takes us unequivocally to disaster."

Persons: Katherine Richardson, Richardson, Ueslei Marcelino, We're, Johan Rockström, I've, Rockström, Riham, David Stanway, Mark Heinrich Our Organizations: University of Copenhagen, REUTERS, Potsdam Institute, Climate Impact, United Nations Global, Thomson Locations: Seca, Uruara, Para State, Brazil, Dubai

Earth is exceeding its “safe operating space for humanity” in six of nine key measurements of its health, and two of the remaining three are headed in the wrong direction, a new study said. Earth’s climate, biodiversity, land, freshwater, nutrient pollution and “novel” chemicals (human-made compounds like microplastics and nuclear waste) are all out of whack, a group of international scientists said in Wednesday’s journal Science Advances. “We are in very bad shape,” said study co-author Johan Rockstrom, director of the Potsdam Institute for Climate Impact Research in Germany. Water went from barely safe to the out-of-bounds category because of worsening river run-off and better measurements and understanding of the problem, Rockstrom said. Political Cartoons View All 1157 ImagesIf Earth can manage these nine factors, Earth could be relatively safe.

Persons: ”, Johan Rockstrom, “, Rockstrom, it’s, –, ” Rockstrom, Jonathan Overpeck, ” Overpeck, Neil Donahue, Duke’s Stuart Pimm, Granger Morgan, ” “ I’ve, ” Morgan, Seth Borenstein Organizations: Potsdam Institute, Climate, Research, Biodiversity, ” University of Michigan, Carnegie Mellon, Twitter, AP Locations: Germany, Paris

☆ ICON to partner with US govt agency to test COVID vaccine candidates
▼ + stars: | 2023-09-13 | by ( ) www.reuters.com time to read: +1 min

Vials labelled "VACCINE Coronavirus COVID-19" and a syringe are seen in front of a displayed U.S. flag in this illustration taken December 11, 2021. REUTERS/Dado Ruvic/Illustration/File Photo Acquire Licensing RightsCompanies Icon Plc FollowBioNTech SE FollowModerna Inc Follow Show more companiesSept 13 (Reuters) - Contract research firm ICON Plc (ICLR.O) said on Wednesday it is partnering with the U.S. government for a clinical trial to test the effectiveness of next generation COVID-19 vaccine candidates. As part of the collaboration with Biomedical Advanced Research and Development Authority, ICON will conduct a mid-stage trial of 10,000 participants to assess the efficacy of a next generation COVID-19 vaccine relative to currently available shots. The U.S. agency will select the vaccine candidate for the trial. The U.S. Food and Drug Administration on Monday authorized updated COVID-19 vaccines from Pfizer (PFE.N)/BioNTech (22UAy.DE) and Moderna (MRNA.O) that target the XBB.1.5 subvariant of the virus.

Persons: Dado Ruvic, Pratik Jain, Saumyadeb Chakrabarty, Shounak Organizations: REUTERS, U.S, Research, Development Authority, U.S . Food, Drug Administration, Pfizer, Moderna, Thomson Locations: U.S, Bengaluru

☆ U.S. Hiring Settles Into a Lower Gear
▼ + stars: | 2023-09-01 | by ( Lydia Depillis | More About Lydia Depillis | ) www.nytimes.com time to read: +2 min

Much of the slowdown has come from industries that are returning to more typical levels after the pandemic’s upheaval. Exhibit A: truck transportation, which grew to serve a stay-at-home online shopping spree and shrank as it died down. Trucking company payrolls flattened out over the past year, which probably masks an outright decline because many contracted owner-operators have also parked their rigs. “With Yellow taking 20-plus-thousand drivers out of the market, it’s a start in getting supply under control.”It’s not just the trucking industry, however. Lately, though, he’s seen more qualified job applicants who need work because their starting dates at law firms have been deferred.

Persons: ”, Kenny Vieth, ” It’s, Kevin Vaughan, It’s, he’s Organizations: Trucking, ACT Research Locations: Chicago

☆ Climate change: Extreme water stress affects a quarter of humanity and it's poised to get worse
▼ + stars: | 2023-08-16 | by ( Hafsa Khalil | ) edition.cnn.com time to read: +5 min

The biggest change in water demand will occur in sub-Saharan Africa according to the report, which projects a 163% increase in water demand by 2050. In North America and Europe, water demand has plateaued, helped by investment in water use efficiency measures. In the US, six states experience extremely high water stress, according to the report. People collect drinking water from in Cape Town on January 19, 2018, during a water crisis which saw the city nearly run dry. The report suggests various measures to prevent water stress spilling into a water crisis.

Persons: ”, Samantha Kuzma, “ I’ve, ” Kuzma, Will Lanzoni, Kuzma, “, Charles, Rodger Bosch, Dieter Gerten, – Organizations: CNN, Ocean Program, UN, Getty, Potsdam Institute, Climate Impact Research Locations: Bahrain, Cyprus, Kuwait, Lebanon, Oman, Lake Mead, Boulder City , Nevada, East, North Africa, Africa, Saharan Africa, North America, Europe, Colorado, Arizona, New Mexico, Charles Iceland, Cape Town, AFP, Vegas, Singapore

☆ Clinical data is a goldmine — but Europe's startups are struggling to grow
▼ + stars: | 2023-08-14 | by ( Riddhi Kanetkar | ) www.businessinsider.com time to read: +5 min

Big Pharma and biotech companies often outsource clinical trials to external companies. Europe's early-stage clinical trials startups are flush with funds but they're struggling to grow. The fate — and market cap — of a biotech company often lies with a successful clinical trial. The COVID-19 pandemic also spotlighted another promising alternative to carry out these trials — startups. While the US touts around a dozen clinical trials unicorns valued at $1 billion or higher, per Dealroom estimates, Europe's startups are lagging behind.

Persons: BEN, Janssen, Christoph Ruedig, Maya Zlatanova, Europe hasn't, Matt Wilson, Wilson, Christoph Massner, it's, Ruedig Organizations: Big Pharma, pharma, Janssen Pharmaceuticals, Tempus, Venture, Albion VC, US, Earlybird Ventures Locations: Europe, New York, American

☆ Charles River says NHP supply snarls to no longer persist near-term
▼ + stars: | 2023-08-09 | by ( ) www.reuters.com time to read: +2 min

Aug 9 (Reuters) - Charles River Laboratories International (CRL.N) beat Wall Street estimates for second-quarter results on Wednesday, as the strong demand for contract researcher's tools and services cushioned the impact of suspended non-human primates' (NHP) shipment. The statement comes after Charles River in February suspended the shipment of NHPs from Cambodia as the Department of Justice and U.S. Fish and Wildlife Service investigated the company over smuggling of wild long-tailed macaques to the United States. The Massachusetts-based company tightened its full-year profit forecast to the range of $10.30 to $10.90 per share, compared with $9.90 to $10.90 previously expected. Excluding items, the company earned $2.69 per share in the quarter ended July 1, beating analysts' average estimate of $2.64 per share.

Persons: Charles River, Charles River's, Vaibhav Sadhamta, Shweta Agarwal Organizations: River Laboratories, Department of Justice, Fish, Wildlife Service, Thomson Locations: United States, NHPs, Cambodia, The Massachusetts

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